Semaglutide – Single GLP-1 Receptor Agonist for Metabolic Research
Semaglutide is a synthetic 31-amino acid peptide analogue of glucagon-like peptide-1 (GLP-1), engineered for metabolic research. As a single GLP-1 receptor agonist with high sequence homology to native GLP-1, it complements G25’s dual-agonist (Tirzepatide) and triple-agonist (Retatrutide) portfolio by providing the classic single-target incretin reference tool for comparative studies.
Key Specifications
- CAS Number: 910463-68-2
- Molecular Formula: C187H291N45O59
- Molecular Weight: 4113.58 g/mol
- Purity: >99% (HPLC verified)
- Appearance: White lyophilized powder
- Storage: 2-8°C (lyophilized)
- Available Sizes: 3mg, 5mg, 10mg per vial
Research Applications
- Glucose homeostasis and insulin secretion studies
- Appetite regulation and satiety signaling
- Body weight regulation and obesity mechanisms
- GLP-1 receptor pharmacology and downstream signaling
- Comparative incretin biology (single vs dual vs triple agonism)
Frequently Asked Questions
What distinguishes Semaglutide from Tirzepatide?
Semaglutide is a single GLP-1 receptor agonist, while Tirzepatide activates both GLP-1 and GIP receptors. Semaglutide serves as the classic single-target incretin reference, useful for isolating GLP-1-specific effects in comparative metabolic research.
What purity does G25 guarantee for Semaglutide?
All Semaglutide batches are independently verified at >99% purity through HPLC and mass spectrometry. Full Certificates of Analysis are available upon request.
How should Semaglutide be stored?
Store lyophilized powder at 2-8°C in a dry, dark environment. After reconstitution, aliquot into single-use portions and store at -20°C. Avoid repeated freeze-thaw cycles.
Is Semaglutide for human use?
No. All G25 products, including Semaglutide, are for research and laboratory use only. They are not intended for human or animal consumption, diagnosis, treatment, or prevention of any condition.















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