CJC 1295 without DAC — GHRH Analogue for Growth Hormone Research
CJC 1295 (modified GRF 1-29) without DAC is a synthetic Growth Hormone-Releasing Hormone (GHRH) analogue consisting of 29 amino acids. Unlike the DAC-conjugated version, CJC 1295 without DAC has a shorter half-life that more closely mimics natural pulsatile GH release patterns, making it ideal for pharmacokinetic and endocrinological research.
Key Specifications
- CAS Number: 863288-34-0
- Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular Weight: 3367.2 g/mol
- Purity: >99.0% (HPLC)
- Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
- Source: Chemical synthesis
- Shelf Life: 2 years
- Available Sizes: 5mg, 10mg per vial
Research Applications
- Growth hormone secretion and pulsatility studies
- IGF-1 pathway and anabolic signaling research
- GHRH receptor pharmacology
- Age-related GH decline investigations
- Comparative peptide pharmacokinetics
Frequently Asked Questions
What is the difference between CJC 1295 with and without DAC?
CJC 1295 without DAC is the base peptide with a half-life of approximately 30 minutes, mimicking natural GHRH pulsatility. The DAC (Drug Affinity Complex) version binds to albumin, extending half-life to several days. Researchers select the version based on their study’s pharmacokinetic requirements.
What purity does RA101 guarantee?
All CJC 1295 without DAC batches exceed 99.0% purity, verified by independent HPLC and mass spectrometry analysis.
How should CJC 1295 be stored?
Store lyophilized powder at 2–8°C. After reconstitution with bacteriostatic water or appropriate buffer, aliquot and freeze at -20°C. Protect from light and moisture.
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