CJC 1295 without DAC: The Complete Research Guide to the GHRH Analogue

What Is CJC 1295 without DAC?

CJC 1295 without DAC is a 29-amino acid GHRH analogue (CAS 863288-34-0, MW 3367.2). Unlike the DAC-conjugated version, it has a shorter half-life mimicking natural pulsatile GH secretion.

Natural Pulsatile Signaling

With a half-life of approximately 30 minutes, CJC 1295 without DAC produces discrete GH pulses rather than sustained elevation. This pulsatile pattern is physiologically relevant for studying natural GH secretion.

Key Specifications at G25

Produced through chemical synthesis with purity exceeding 99.0 percent. Available in 5mg and 10mg vials. Two-year shelf life when stored at 2 to 8 degrees Celsius. Appearance: white lyophilized powder.

Research Applications

Growth hormone pulsatility studies, IGF-1 pathway and anabolic signaling, GHRH receptor pharmacology, age-related GH decline, and comparative peptide pharmacokinetics.

Sequence

Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2.

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